{"id":7536,"date":"2025-08-21T05:01:08","date_gmt":"2025-08-21T05:01:08","guid":{"rendered":"https:\/\/www.nrc.gov.lk\/?page_id=7536"},"modified":"2025-09-23T08:36:33","modified_gmt":"2025-09-23T08:36:33","slug":"standardization-and-preclinical-investigation-of-traditional-herbal-formula-for-the-management-of-chronic-kidney-disease","status":"publish","type":"page","link":"https:\/\/www.nrc.gov.lk\/index.php\/standardization-and-preclinical-investigation-of-traditional-herbal-formula-for-the-management-of-chronic-kidney-disease\/","title":{"rendered":"Standardization and preclinical investigation of traditional herbal formula for the management of chronic kidney disease"},"content":{"rendered":"<section class=\"kc-elm kc-css-550520 kc_row\"><div class=\"kc-row-container  kc-container\"><div class=\"kc-wrap-columns\"><div class=\"kc-elm kc-css-49431 kc_col-sm-12 kc_column kc_col-sm-12\"><div class=\"kc-col-container\"><div class=\"kc-elm kc-css-19165 kc_text_block\"><\/p>\n<p><style type=\"text\/css\"><span data-mce-type=\"bookmark\" style=\"display: inline-block; width: 0px; overflow: hidden; line-height: 0;\" class=\"mce_SELRES_start\">\ufeff<\/span>@media only screen and (min-width: 1000px) and (max-width: 5000px){body.kc-css-system .kc-css-549572{width: 33.33%;}body.kc-css-system .kc-css-2760201{width: 33.33%;}body.kc-css-system .kc-css-3608739{width: 33.33%;}body.kc-css-system .kc-css-1460741{width: 50%;}body.kc-css-system .kc-css-614051{width: 50%;}body.kc-css-system .kc-css-2958748{width: 100%;}}body.kc-css-system .kc-css-351858{height: 20px;}body.kc-css-system .kc-css-3734677{padding-top: 50px;padding-bottom: 50px;}body.kc-css-system .kc-css-2157947 ,body.kc-css-system .kc-css-2157947 p{color: #000000;}body.kc-css-system .kc-css-2157947{background: #ffffff;}body.kc-css-system .kc-css-614051{padding-left: 8%;}@media only screen and (max-width: 999px){body.kc-css-system .kc-css-1460741{margin-left: 0%;width: 100%;}body.kc-css-system .kc-css-614051{margin-left: 0%;width: 100%;padding-top: 10px;padding-left: 15px;}}<\/style>\n<\/p>\n<section class=\"kc-elm kc-css-4298318 kc_row\">\n<div class=\"kc-row-container kc-container\">\n<div class=\"kc-wrap-columns\">\n<div class=\"kc-elm kc-css-646620 kc_col-sm-12 kc_column kc_col-sm-12\">\n<div class=\"kc-col-container\">\n<div class=\"kc-elm kc-css-2474525 kc-title-wrap \">\n<h2 class=\"kc_title page-title font-md lil-line\">Standardization and preclinical investigation of traditional herbal formula for the management of chronic kidney disease<\/h2>\n<\/div>\n<div class=\"kc-elm kc-css-310475\" style=\"height: 20px; clear: both; width: 100%;\">\u00a0<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"kc-elm kc-css-4006592 kc_row\">\n<div class=\"kc-row-container kc-container\">\n<div class=\"kc-wrap-columns\">\n<div class=\"kc-elm kc-css-549572 kc_col-sm-4 kc_column kc_col-sm-4\">\n<div class=\"kc-col-container\">\n<div class=\"kc-elm kc-css-351858 kc_box_wrap \">\n<div>\n<div class=\"one-one\">\n<p><b>NRC Grant No:<\/b>\u00a0 \u00a0 NRC PPP 23-07<span style=\"color: #000000; font-family: Arial, Helvetica, sans-serif; font-size: 13.3333px; text-align: start;\">\u00a0<\/span><\/p>\n<p><b>Research Institute:\u00a0<\/b>University of Kelaniya<\/p>\n<p><b>Amount Funded:<\/b>\u00a0 \u00a0Rs. 3200000.oo<\/p>\n<p><b>Date of Awarded:<\/b>\u00a0 15th December 2023<\/p>\n<p><b>End Date:<\/b>\u00a014th December 2025<\/p>\n<p><strong>Status:<\/strong>\u00a0 Ongoing<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"kc-elm kc-css-2760201 kc_col-sm-4 kc_column kc_col-sm-4\">\n<div class=\"kc-col-container\">\n<article class=\"sabbi-thumlinepost-card solitude-bg__x kc-elm kc-css-2380020\">\n<figure class=\"sabbi-thumlinepost-card-figure\"><img loading=\"lazy\" decoding=\"async\" class=\"img-responsive img-thumpost\" src=\"http:\/\/imcedu.com\/new\/wp-content\/uploads\/2021\/03\/profile.jpg\" alt=\"\" width=\"271\" height=\"211\" \/><\/figure>\n<div class=\"sabbi-thumlinepost-card-meta\">\n<h2 class=\"info-box-title ht-5\">Principal Investigator<\/h2>\n<p>Prof. Priyani Ashoka Paranagama<br \/>University of Kelaniya<\/p>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<div class=\"kc-elm kc-css-3608739 kc_col-sm-4 kc_column kc_col-sm-4\">\n<div class=\"kc-col-container\">\n<article class=\"sabbi-thumlinepost-card solitude-bg__x kc-elm kc-css-2495362\">\n<figure class=\"sabbi-thumlinepost-card-figure\"><img loading=\"lazy\" decoding=\"async\" class=\"img-responsive img-thumpost\" src=\"http:\/\/imcedu.com\/new\/wp-content\/uploads\/2021\/03\/profile.jpg\" alt=\"\" width=\"271\" height=\"211\" \/><\/figure>\n<div class=\"sabbi-thumlinepost-card-meta\">\n<h2 class=\"info-box-title ht-5\">Deputy Principal Investigator<\/h2>\n<p>Mrs. Lankani Hettigoda<br \/>Hettigoda Industries (Pvt) Limited<\/p>\n<\/div>\n<\/article>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"kc-elm kc-css-3734677 kc_row\">\n<div class=\"kc-row-container kc-container\">\n<div class=\"kc-wrap-columns\">\n<div class=\"kc-elm kc-css-1460741 kc_col-sm-6 kc_column kc_col-sm-6\">\n<div class=\"kc-col-container\">\n<div class=\"kc-elm kc-css-2157947 kc_text_block\">\n<h2>Summary<\/h2>\n<p>CKD incurs enormous direct (dialysis, kidney transplantation) and indirect costs resulting in a tremendous economic burden. CKD is not publicly funded in many countries. Therefore, CKD is linked with economic hardships, poor quality of life, and premature deaths. The availability of a commercially viable, cost-effective product to manage CKD will help to solve the cost crisis in the healthcare Development of traditional herbal formula with scientific validation will help to earn more foreign exchange to the country. This study is focused on investigating the nephroprotective efficacy of the herbal distillate prepared according to the ayurvedic heritage of Hettigoda family.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"kc-elm kc-css-614051 kc_col-sm-6 kc_column kc_col-sm-6\">\n<div class=\"kc-col-container\">\n<div class=\"kc-elm kc-css-3445199 kc_text_block\">\n<h2>Objectives<\/h2>\n<ul>\n<li>To evaluate the phytochemical analysis, biochemical efficacy, cytotoxicity and nephroprotective activity of the traditional herbal formulation in vitro for the management and treatment of kidney disease using a kidney cell line.<\/li>\n<li>To evaluate the shelf life of the herbal distillate to confirm the shelf life<\/li>\n<li>To investigate the nephroprotective activity of the traditional preparations against in vivo in a Wistar rat model.<\/li>\n<li>To open a new income avenue to increase the foreign exchange in the country<\/li>\n<\/ul>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"kc-elm kc-css-263584 kc_row\">\n<div class=\"kc-row-container kc-container\">\n<div class=\"kc-wrap-columns\">\n<div class=\"kc-elm kc-css-2958748 kc_col-sm-12 kc_column kc_col-sm-12\">\n<div class=\"kc-col-container\">\n<div class=\"kc-elm kc-css-333070 kc_text_block\">\n<h2>Major Equipment Facilitated by Grant<\/h2>\n<p>N\/A<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"kc-elm kc-css-3287319 kc_row\">\n<div class=\"kc-row-container kc-container\">\n<div class=\"kc-wrap-columns\">\n<div class=\"kc-elm kc-css-864877 kc_col-sm-12 kc_column kc_col-sm-12\">\n<div class=\"kc-col-container\">\n<div class=\"kc-elm kc-css-2310744\" style=\"height: 20px; clear: both; width: 100%;\">\u00a0<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<section class=\"kc-elm kc-css-2835418 kc_row\">\n<div class=\"kc-row-container kc-container\">\n<div class=\"kc-wrap-columns\">\n<div class=\"kc-elm kc-css-2776938 kc_col-sm-12 kc_column kc_col-sm-12\">\n<div class=\"kc-col-container\">\u00a0<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n<p>\n<\/div><\/div><\/div><\/div><\/div><\/section>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":250,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-7536","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/pages\/7536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/comments?post=7536"}],"version-history":[{"count":5,"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/pages\/7536\/revisions"}],"predecessor-version":[{"id":7585,"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/pages\/7536\/revisions\/7585"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/media\/250"}],"wp:attachment":[{"href":"https:\/\/www.nrc.gov.lk\/index.php\/wp-json\/wp\/v2\/media?parent=7536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}