{"id":6098,"date":"2022-06-30T17:14:37","date_gmt":"2022-06-30T17:14:37","guid":{"rendered":"https:\/\/www.nrc.gov.lk\/?page_id=6098"},"modified":"2022-06-30T17:14:37","modified_gmt":"2022-06-30T17:14:37","slug":"investigation-of-cultivar-dependent-dynamics-of-seed-metal-ion-content-and-identification-of-prospective-genetic-candidates-for-nutritional-quality-improvement-in-sri-lankan-rice-germplasm","status":"publish","type":"page","link":"https:\/\/www.nrc.gov.lk\/index.php\/investigation-of-cultivar-dependent-dynamics-of-seed-metal-ion-content-and-identification-of-prospective-genetic-candidates-for-nutritional-quality-improvement-in-sri-lankan-rice-germplasm\/","title":{"rendered":"Investigation of cultivar dependent dynamics of seed metal ion content and identification of prospective genetic candidates for nutritional quality improvement in Sri Lankan rice germplasm"},"content":{"rendered":"

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Investigation of cultivar dependent dynamics of seed metal ion content and identification of prospective genetic candidates for nutritional quality improvement in Sri Lankan rice germplasm<\/h2>\n<\/div>\n
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NRC Grant No:<\/text><\/b>  19-054<\/text><\/p>

Research Institute:  <\/text><\/b>The Open University of Sri Lanka<\/text><\/p>

Area of Research:<\/text><\/strong> Plant Biotechnology <\/text><\/p>

Total Budget:  <\/text><\/b>7,918,000<\/text><\/p>

Email:<\/text><\/strong> spsen@ou.ac.lk<\/text><\/p>

Start date:  <\/text><\/b>26th Sep 2019<\/text><\/p>

End Date:<\/text><\/strong> 26th Sep 2022<\/text><\/p>

Duration:<\/text><\/strong> 36 months<\/text><\/p>

Status:<\/text><\/strong>  Ongoing<\/text><\/p><\/div><\/div><\/div><\/div><\/div>

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Principal Investigator\r\n<\/h2>

Dr. Prasad Senadheera
\nThe Open University of Sri Lanka
\nspsen@ou.ac.lk<\/p>\n<\/div>\n <\/article><\/div><\/div>

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<\/h2><\/div>\n <\/article><\/div><\/div><\/div><\/div><\/section>
<\/p>\n

Summary<\/h2>\n

Hidden hunger induced by micronutrient deficiencies and exposure to heavy metal are significant health challenges of the human at present. As such, United Nations (UN) declared that tackling micronutrient deficiencies is one of the sustainable development goals to be achieved by 2035. Being staple crop, nutritional quality of rice plays a key role in the life quality of its consumers. Rice is an accumulator of many minerals including Fe, Zn, Se, As, Cd. Rice is recognized as one of the major pathways through which biofortification of micronutrients such Fe, Zn, Se and bioaccumulation of heavy metal occur. No systematic study with long term plan has been done on the vastly diverse Sri Lankan rice cultivars on these aspects. This proposed research envisages to identify Sri Lankan rice cultivars that accumulate varying amounts of metal ions in the seeds. By deploying genotyped pure lines of 212 Sri Lankan rice cultivars for the first time, this research project plans to identify gens and parents for improving rice with higher accumulation of micronutrients while reducing heavy metals in the seeds. In addition, basis for discovering genes for making \u2018healthy rice\u2019 is provided through this project. Biofortification is the most affordable and sustainable solution for the hidden hunger among rice consumers who are from resource poor backgrounds. Outcome of this research will have significant impact on improving nutritional quality and food safety of rice in Sri Lanka and can be extended to global scale. Moreover, trans-national collaboration established with RRDISL+ and other research Universities* will facilitate the effective sharing of knowledge, skills and resources to enrich rice research in Sri Lanka.<\/p>\n

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Objectives<\/h2>\n

1)\u00a0\u00a0\u00a0 Determination of patterns of metal (Fe, Zn, Co, Mn, Pb, Al, As, Cd ) accumulation in the grain of 212 Sri Lankan rice varieties with known genomic identity (established in IRRI)<\/p>\n

2)\u00a0\u00a0\u00a0 Carry out genome wide association study (GWAS) using the 6K short nucleotide polymorphic (SNP) data on these 212 varieties to identify the prospective polymorphic genomic regions.<\/p>\n

3)\u00a0\u00a0\u00a0 Identification of promising genomic areas associated with inclusion\/ exclusion of metal ions through comprehensive bioinformatics analysis 4)\u00a0\u00a0\u00a0 Make available data for designing rice improvement programmes for nutritional quality\u00a0 5)\u00a0\u00a0\u00a0 Initiate functional validation of promising candidate genes through near isogenic lines (NIL) or allele association studies.<\/p>\n

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<\/p>\n

Major Equipment Facilitated by Grant<\/h2>\n

N\/A<\/p>\n

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<\/p>\n

\nDesignation<\/strong><\/p>\n

Principal Investigator (PI)<\/p>\n

Deputy Principal Investigator (DPI)<\/p>\n

Co- investigator<\/p>\n

Co- investigator<\/p>\n

Co- investigator<\/p>\n

Co- investigator<\/p>\n

Co- investigator<\/p>\n

Co- investigator<\/p>\n

Co- investigator<\/p>\n

\n<\/div><\/div><\/div>

<\/p>\n

\nName<\/strong><\/p>\n

Dr. Meththika Vithanage<\/p>\n

Dr. B.C.L. Athapattu<\/p>\n

Prof. Ajith de Alwis<\/p>\n

Dr. Mahinsasa Narayana<\/p>\n

Dr. A. K. Karunarathna<\/p>\n

Prof. Ranji Ranjithan<\/p>\n

Dr. Mahinsasa Narayana<\/p>\n

Prof. Taeho Lee<\/p>\n

Dr. Maneesha P. Ginige<\/p>\n

\n<\/div><\/div><\/div>

<\/p>\n

\nInstitute<\/b><\/p>\n

University of Sri Jayewardenepura<\/p>\n

The Open University of Sri Lanka<\/p>\n

University of Moratuwa<\/p>\n

University of Moratuwa<\/p>\n

University of Peradeniya<\/p>\n

Waste Management Authority, Western Province<\/p>\n

North Carolina State University, USA<\/p>\n

Pusan National University Korea<\/p>\n

CSIRO, Australia<\/p>\n

\n<\/div><\/div><\/div><\/div><\/div><\/section>

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